Dimethyl Sulfoxide → (7RS,9aRS)-[2-(7-Amino-2-furan-2-yl-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)-octahydro-pyrido[1,2-a]pyrazin-7-yl]-methanol

HRID 1129915Notes

Reaction equation

HRID 1129915 reaction equation
[CH2:20]1[CH:21]2[N:22]([CH2:23][CH2:24][NH:25]1)[CH2:26][CH:27]([CH2:30][OH:31])[CH2:28][CH2:29]2.[CH3:32][S:33]([CH3:34])=[O:35].[o:1]1[c:2](-[c:6]2[n:7][n:8]3[c:9]([n:10][c:11]([S:15]([CH3:16])(=[O:17])=[O:18])[n:12][c:13]3[NH2:14])[n:19]2)[cH:3][cH:4][cH:5]1>>[o:1]1[c:2](-[c:6]2[n:7][n:8]3[c:9]([n:10][c:11]([N:25]4[CH2:20][CH:21]5[N:22]([CH2:23][CH2:24]4)[CH2:26][CH:27]([CH2:30][OH:31])[CH2:28][CH2:29]5)[n:12][c:13]3[NH2:14])[n:19]2)[cH:3][cH:4][cH:5]1

Participants

4

Reactant 3

HCID 679Dimethyl SulfoxideHCID 99708822-(Furan-2-yl)-5-(methylsulfonyl)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-7-amineHCID 12985539(Octahydro-1H-pyrido[1,2-A]pyrazin-7-YL)methanol

Product 1

HCID 11268712(7RS,9aRS)-[2-(7-Amino-2-furan-2-yl-[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)-octahydro-pyrido[1,2-a]pyrazin-7-yl]-methanol

Sources & evidence

ORD record
ord-f04cab5d752b4686b0db824120a9d1b3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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