tert-butyl N-(4-oxocyclohexyl)carbamate → {4-{3-[2-(3-Trifluoromethyl-benzoylamino)-acetylamino]-azetidin-1-yl}-cyclohexyl)-carbamic acid tert-butyl ester

HRID 1130053Notes

Reaction equation

HRID 1130053 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH:8]1[CH2:9][CH2:10][C:11](=[O:14])[CH2:12][CH2:13]1)=[O:15].[NH:16]1[CH2:17][CH:18]([NH:20][C:21](=[O:22])[CH2:23][NH:24][C:25]([c:26]2[cH:27][c:28]([C:32]([F:33])([F:34])[F:35])[cH:29][cH:30][cH:31]2)=[O:36])[CH2:19]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([NH:7][CH:8]1[CH2:9][CH2:10][CH:11]([N:16]2[CH2:17][CH:18]([NH:20][C:21](=[O:22])[CH2:23][NH:24][C:25]([c:26]3[cH:27][c:28]([C:32]([F:33])([F:34])[F:35])[cH:29][cH:30][cH:31]3)=[O:36])[CH2:19]2)[CH2:12][CH2:13]1)=[O:15]

Participants

3

Reactant 2

HCID 1512535tert-butyl N-(4-oxocyclohexyl)carbamateHCID 59361594N-(azetidin-3-ylcarbamoylmethyl)-3-trifluoromethyl-benzamide

Product 1

HCID 59541119{4-{3-[2-(3-Trifluoromethyl-benzoylamino)-acetylamino]-azetidin-1-yl}-cyclohexyl)-carbamic acid tert-butyl ester

Sources & evidence

ORD record
ord-adba18251ef7480688862339f3548b2e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

Loading…