Carbonate Ion → 2-Chloro-N-(2-(pyrimidin-2-yl)phenyl)-5-(trifluoromethyl)pyridin-4-amine
Reaction equation
[C:26](=[O:27])([O-:28])[O-:29].[Cl:1][c:2]1[n:3][cH:4][c:5]([C:9]([F:10])([F:11])[F:12])[c:6]([I:8])[cH:7]1.[Cs+:30].[Cs+:31].[O:32]1[CH2:33][CH2:34][O:35][CH2:36][CH2:37]1.[O:40]=[C:41]([CH:42]=[CH:43][c:44]1[cH:45][cH:46][cH:47][cH:48][cH:49]1)[CH:50]=[CH:51][c:52]1[cH:53][cH:54][cH:55][cH:56][cH:57]1.[O:58]=[C:59]([CH:60]=[CH:61][c:62]1[cH:63][cH:64][cH:65][cH:66][cH:67]1)[CH:68]=[CH:69][c:70]1[cH:71][cH:72][cH:73][cH:74][cH:75]1.[O:76]=[C:77]([CH:78]=[CH:79][c:80]1[cH:81][cH:82][cH:83][cH:84][cH:85]1)[CH:86]=[CH:87][c:88]1[cH:89][cH:90][cH:91][cH:92][cH:93]1.[Pd:38].[Pd:39].[n:13]1[c:14](-[c:19]2[c:20]([NH2:21])[cH:22][cH:23][cH:24][cH:25]2)[n:15][cH:16][cH:17][cH:18]1>>[Cl:1][c:2]1[n:3][cH:4][c:5]([C:9]([F:10])([F:11])[F:12])[c:6]([NH:21][c:20]2[c:19](-[c:14]3[n:13][cH:18][cH:17][cH:16][n:15]3)[cH:25][cH:24][cH:23][cH:22]2)[cH:7]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-5acad36a5dfc4b9fba2affaf9bd3811e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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