Ethyl 3-(3-chlorophenyl)prop-2-ynoate → 7-(2-{1-[1-(3-Chloro-phenyl)-2-ethoxycarbonyl-vinyl]-1H-indol-5-yloxy}-ethyl)-3,4-dihydro-2H-[1,8]naphthyridine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:15]([CH3:16])([CH3:17])([CH3:18])[O:19][C:20](=[O:21])[N:22]1[CH2:23][CH2:24][CH2:25][c:26]2[cH:27][cH:28][c:29]([CH2:32][CH2:33][O:34][c:35]3[cH:36][c:37]4[cH:38][cH:39][nH:40][c:41]4[cH:42][cH:43]3)[n:30][c:31]21.[CH2:1]([CH3:2])[O:3][C:4]([C:5]#[C:6][c:7]1[cH:8][c:9]([Cl:13])[cH:10][cH:11][cH:12]1)=[O:14]>>[CH2:1]([CH3:2])[O:3][C:4]([CH:5]=[C:6]([c:7]1[cH:8][c:9]([Cl:13])[cH:10][cH:11][cH:12]1)[n:40]1[cH:39][cH:38][c:37]2[cH:36][c:35]([O:34][CH2:33][CH2:32][c:29]3[cH:28][cH:27][c:26]4[c:31]([n:30]3)[N:22]([C:20]([O:19][C:15]([CH3:16])([CH3:17])[CH3:18])=[O:21])[CH2:23][CH2:24][CH2:25]4)[cH:43][cH:42][c:41]21)=[O:14]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-0c48b65b9778458bb32a2696add0ce64
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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