Methanol → 3-(8-Amino-7-methoxy-1,2,4,5-tetrahydro-3-benzazepin-3-yl)-1,1,1-trifluoropropan-2-ol
Reaction equation
[CH3:27][OH:28].[F:1][C:2]([CH:3]([CH2:4][N:5]1[CH2:6][CH2:7][c:8]2[c:9]([cH:12][c:13]([O:19][CH3:20])[c:14]([N+:16]([O-:17])=[O:18])[cH:15]2)[CH2:10][CH2:11]1)[OH:21])([F:22])[F:23].[H:25][H:26].[OH2:24].[Pd:29]>>[F:1][C:2]([CH:3]([CH2:4][N:5]1[CH2:6][CH2:7][c:8]2[c:9]([cH:12][c:13]([O:19][CH3:20])[c:14]([NH2:16])[cH:15]2)[CH2:10][CH2:11]1)[OH:21])([F:22])[F:23]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-db5480d652da4a869d63714e59f6d344
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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