1-Chloro-2-iodo-4-(trifluoromethyl)benzene → 8-(2-Chloro-benzenesulfonyl)-2-(2-chloro-5-trifluoromethyl-phenyl)-2,8-diaza-spiro[4.5]decan-1-one
Reaction equation
[Cl:1][c:2]1[c:3]([S:8](=[O:9])(=[O:10])[N:11]2[CH2:12][CH2:13][C:14]3([CH2:15][CH2:16][NH:17][C:18]3=[O:19])[CH2:20][CH2:21]2)[cH:4][cH:5][cH:6][cH:7]1.[Cl:22][c:23]1[c:24]([I:33])[cH:25][c:26]([C:29]([F:30])([F:31])[F:32])[cH:27][cH:28]1>>[Cl:1][c:2]1[c:3]([S:8](=[O:9])(=[O:10])[N:11]2[CH2:12][CH2:13][C:14]3([CH2:15][CH2:16][N:17]([c:24]4[c:23]([Cl:22])[cH:28][cH:27][c:26]([C:29]([F:30])([F:31])[F:32])[cH:25]4)[C:18]3=[O:19])[CH2:20][CH2:21]2)[cH:4][cH:5][cH:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-a5e6f5bc7dfd488d9aa2866d28c967df
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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