3-Quinolinecarboxylic acid, 4-chloro-8-methoxy-, ethyl ester → 4-(4,4-Difluoro-cyclohexylamino)-8-methoxy-quinoline-3-carboxylic acid ethyl ester
Reaction equation
[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[cH:7][n:8][c:9]2[c:10]([O:17][CH3:18])[cH:11][cH:12][cH:13][c:14]2[c:15]1[Cl:16].[F:19][C:20]1([F:27])[CH2:21][CH2:22][CH:23]([NH2:26])[CH2:24][CH2:25]1>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[cH:7][n:8][c:9]2[c:10]([O:17][CH3:18])[cH:11][cH:12][cH:13][c:14]2[c:15]1[NH:26][CH:23]1[CH2:22][CH2:21][C:20]([F:19])([F:27])[CH2:25][CH2:24]1Participants
3
Sources & evidence
- ORD record
- ord-bfa419b046794ff9a329d2b3e97be6e5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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