Potassium Cation → tert-Butyl 4-(2-fluoroethyl)piperazine-1-carboxylate

HRID 113101Notes

Reaction equation

HRID 113101 reaction equation
[Br:28][CH2:29][CH2:30][F:31].[C:14](=[O:15])([O-:16])[O-:17].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][NH:11][CH2:12][CH2:13]1.[CH2:22]1[O:23][CH2:24][CH2:25][O:26][CH2:27]1.[I-:21].[K+:18].[K+:19].[Na+:20]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([CH2:29][CH2:30][F:31])[CH2:12][CH2:13]1

Participants

8

Reactant 7

HCID 813Potassium Cation2×HCID 923Sodium ionHCID 129822-Fluoroethyl bromideHCID 19660Carbonate IonHCID 30165Iodide IonHCID 312751,4-DioxaneHCID 143452tert-Butyl piperazine-1-carboxylate

Product 1

HCID 21082715tert-Butyl 4-(2-fluoroethyl)piperazine-1-carboxylate

Sources & evidence

ORD record
ord-4511f240472e484aa9bc835458afeee4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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