1,2-Dimethoxyethane → 6-[1-(4-Cyano-phenyl)-1H-1,2,3-triazol-5-yl]-N,5-dimethyl-3-oxo-4-[3-(trifluoromethyl)-phenyl]-3,4-dihydro-pyrazine-2-carboxamide

HRID 1131044Notes

Reaction equation

HRID 1131044 reaction equation
[Br:27][c:28]1[c:29]([CH3:49])[n:30](-[c:39]2[cH:40][c:41]([C:45]([F:46])([F:47])[F:48])[cH:42][cH:43][cH:44]2)[c:31](=[O:38])[c:32]([C:34](=[O:35])[NH:36][CH3:37])[n:33]1.[CH2:1]([Sn:2]([CH2:3][CH2:4][CH2:5][CH3:19])([c:6]1[cH:7][n:8][n:9][n:10]1-[c:11]1[cH:12][cH:13][c:14]([C:15]#[N:16])[cH:17][cH:18]1)[CH2:20][CH2:21][CH2:22][CH3:23])[CH2:24][CH2:25][CH3:26].[CH3:50][O:51][CH2:52][CH2:53][O:54][CH3:55]>>[c:6]1(-[c:28]2[c:29]([CH3:49])[n:30](-[c:39]3[cH:40][c:41]([C:45]([F:46])([F:47])[F:48])[cH:42][cH:43][cH:44]3)[c:31](=[O:38])[c:32]([C:34](=[O:35])[NH:36][CH3:37])[n:33]2)[cH:7][n:8][n:9][n:10]1-[c:11]1[cH:12][cH:13][c:14]([C:15]#[N:16])[cH:17][cH:18]1

Participants

4

Reactant 3

HCID 80711,2-DimethoxyethaneHCID 667385044-(5-Tributylstannanyl-[1,2,3]triazol-1-yl)-benzonitrileHCID 667386596-Bromo-N,5-dimethyl-3-oxo-4-[3-(trifluoromethyl)phenyl]-3,4-dihydropyrazine-2-carboxamide

Product 1

HCID 248901426-[1-(4-Cyano-phenyl)-1H-1,2,3-triazol-5-yl]-N,5-dimethyl-3-oxo-4-[3-(trifluoromethyl)-phenyl]-3,4-dihydro-pyrazine-2-carboxamide

Sources & evidence

ORD record
ord-b51fe1fa562b4f1191f3c41774384c3e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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