5-(Chloromethyl)pyrimidine → 13-Bromo-3-(pyridin-3-ylmethyl)-7-(pyrimidin-5-ylmethoxy)-1-azatetracyclo[7.6.1.05,16.010,15]hexadeca-2,5,7,9(16),10(15),11,13-heptaen-4-one

HRID 1131195Notes

Reaction equation

HRID 1131195 reaction equation
[Br:1][c:2]1[cH:3][c:4]2[n:5]3[c:6]4[c:7]([cH:8][c:9]([OH:15])[cH:10][c:11]4[c:12]2[cH:13][cH:14]1)[c:16](=[O:26])[c:17]([CH2:19][c:20]1[cH:21][n:22][cH:23][cH:24][cH:25]1)[cH:18]3.[n:27]1[cH:28][n:29][cH:30][c:31]([CH2:33][Cl:34])[cH:32]1>>[Br:1][c:2]1[cH:3][c:4]2[n:5]3[c:6]4[c:7]([cH:8][c:9]([O:15][CH2:33][c:31]5[cH:30][n:29][cH:28][n:27][cH:32]5)[cH:10][c:11]4[c:12]2[cH:13][cH:14]1)[c:16](=[O:26])[c:17]([CH2:19][c:20]1[cH:21][n:22][cH:23][cH:24][cH:25]1)[cH:18]3

Participants

3

Reactant 2

HCID 147202965-(Chloromethyl)pyrimidineHCID 212528709-bromo-2-hydroxy-5-(3-pyridylmethyl)-4H-pyrido [3,2,1-jk]carbazole-4-one

Product 1

HCID 1936487013-Bromo-3-(pyridin-3-ylmethyl)-7-(pyrimidin-5-ylmethoxy)-1-azatetracyclo[7.6.1.05,16.010,15]hexadeca-2,5,7,9(16),10(15),11,13-heptaen-4-one

Sources & evidence

ORD record
ord-b76a979437ad470d94aa858f711fb487
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

Loading…