Dichloromethane → 4-(4'-Difluoromethoxy-biphenyl-4-ylsulphanylmethyl)-5-methyl-furan-2-carboxylic acid methyl ester

HRID 1131397Notes

Reaction equation

HRID 1131397 reaction equation
[C:42](=[O:43])([O-:44])[O-:45].[CH3:4][O:5][C:6](=[O:7])[c:8]1[o:9][c:10]([CH3:30])[c:11]([CH2:13][S:14][c:15]2[cH:16][cH:17][c:18]([B:21]3[O:22][C:23]([CH3:24])([CH3:25])[C:26]([CH3:27])([CH3:28])[O:29]3)[cH:19][cH:20]2)[cH:12]1.[Cl:1][CH2:2][Cl:3].[Cs+:46].[Cs+:47].[F:31][CH:32]([O:33][c:34]1[cH:35][cH:36][c:37]([I:40])[cH:38][cH:39]1)[F:41].[O:48]1[CH2:49][CH2:50][O:51][CH2:52][CH2:53]1>>[CH3:4][O:5][C:6](=[O:7])[c:8]1[o:9][c:10]([CH3:30])[c:11]([CH2:13][S:14][c:15]2[cH:16][cH:17][c:18](-[c:37]3[cH:36][cH:35][c:34]([O:33][CH:32]([F:31])[F:41])[cH:39][cH:38]3)[cH:19][cH:20]2)[cH:12]1

Participants

7

Reactant 6

HCID 6344DichloromethaneHCID 19660Carbonate IonHCID 312751,4-DioxaneHCID 104967Cesium cation2×HCID 27370081-(Difluoromethoxy)-4-iodobenzeneHCID 588241845-Methyl-4-[4-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenylsulphanylmethyl]-furan-2-carboxylic acid methyl ester

Product 1

HCID 588241974-(4'-Difluoromethoxy-biphenyl-4-ylsulphanylmethyl)-5-methyl-furan-2-carboxylic acid methyl ester

Sources & evidence

ORD record
ord-47167a0d504d4c22862fca910ea64661
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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