3-Chloro-4-fluorophenylboronic Acid (contains varying amounts of Anhydride) → 6'-(3-Chloro-4-fluorophenyl)-5-methyl-2'',3'',5'',6''-tetrahydro-3'H-dispiro[imidazole-2,1 indene-2',4''-pyran]-4-amine

HRID 1131488Notes

Reaction equation

HRID 1131488 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:15]([cH:16]1)[C:8]1([C:7]3([CH2:6]2)[CH2:17][CH2:18][O:19][CH2:20][CH2:21]3)[N:9]=[C:10]([CH3:14])[C:11]([NH2:13])=[N:12]1.[Cl:22][c:23]1[cH:24][c:25]([B:30]([OH:31])[OH:32])[cH:26][cH:27][c:28]1[F:29]>>[c:2]1(-[c:25]2[cH:24][c:23]([Cl:22])[c:28]([F:29])[cH:27][cH:26]2)[cH:3][cH:4][c:5]2[c:15]([cH:16]1)[C:8]1([C:7]3([CH2:6]2)[CH2:17][CH2:18][O:19][CH2:20][CH2:21]3)[N:9]=[C:10]([CH3:14])[C:11]([NH2:13])=[N:12]1

Participants

3

Reactant 2

HCID 27346603-Chloro-4-fluorophenylboronic Acid (contains varying amounts of Anhydride)HCID 573858806'-Bromo-5-methyl-2'',3'',5'',6''-tetrahydro-3'H-dispiro[imidazole-2,1'-indene-2',4''-pyran]-4-amine

Product 1

HCID 573858826'-(3-Chloro-4-fluorophenyl)-5-methyl-2'',3'',5'',6''-tetrahydro-3'H-dispiro[imidazole-2,1 indene-2',4''-pyran]-4-amine

Sources & evidence

ORD record
ord-4cf6e92cfaab48078c4d034c99645b76
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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