Methanol → Tert-butyl 4-hydroxypiperidine-1-carboxylate

HRID 1132083Notes

Reaction equation

HRID 1132083 reaction equation
[BH4-:15].[CH3:17][OH:18].[Na+:16].[O:1]=[C:2]1[CH2:3][CH2:4][N:5]([C:8](=[O:9])[O:10][C:11]([CH3:12])([CH3:13])[CH3:14])[CH2:6][CH2:7]1>>[OH:1][CH:2]1[CH2:3][CH2:4][N:5]([C:8](=[O:9])[O:10][C:11]([CH3:12])([CH3:13])[CH3:14])[CH2:6][CH2:7]1

Participants

5

Reactant 4

HCID 887MethanolHCID 923Sodium ionHCID 28123BorohydrideHCID 735900tert-Butyl 4-oxopiperidine-1-carboxylate

Product 1

HCID 643502Tert-butyl 4-hydroxypiperidine-1-carboxylate

Sources & evidence

ORD record
ord-dd110fb7a5c14aa5ad11abcb21db0620
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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