Pyridine → 3-[(2,6-Dichloro-4-phenylmethoxyphenyl)methyl]-1-[4-tri(propan-2-yl)silyloxypiperidin-1-yl]pyrrolidin-2-one
Reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][c:11]([Cl:30])[c:12]([CH2:13][CH:14]2[C:15](=[O:26])[N:16]([N:19]3[CH2:20][CH2:21][CH:22]([OH:25])[CH2:23][CH2:24]3)[CH2:17][CH2:18]2)[c:27]([Cl:29])[cH:28]1.[CH:37]([CH3:38])([CH3:39])[Si:40]([CH:41]([CH3:42])[CH3:43])([CH:44]([CH3:45])[CH3:46])[O:47][S:48]([C:49]([F:50])([F:51])[F:52])(=[O:53])=[O:54].[Cl:55][CH2:56][Cl:57].[cH:31]1[cH:32][cH:33][n:34][cH:35][cH:36]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][c:9]1[cH:10][c:11]([Cl:30])[c:12]([CH2:13][CH:14]2[C:15](=[O:26])[N:16]([N:19]3[CH2:20][CH2:21][CH:22]([O:25][Si:40]([CH:37]([CH3:38])[CH3:39])([CH:41]([CH3:42])[CH3:43])[CH:44]([CH3:45])[CH3:46])[CH2:23][CH2:24]3)[CH2:17][CH2:18]2)[c:27]([Cl:29])[cH:28]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-0d1010a56e2d4f3e90116b7746ed8e50
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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