2-(2-Amino-thiazol-4-yl)-benzoic acid → N-[[2-[2-(2-amino-1,3-thiazol-4-yl)benzoyl]-2-azabicyclo[3.1.0]hexan-3-yl]methyl]-2,3-dihydro-1,4-benzodioxine-5-carboxamide

HRID 1132535Notes

Reaction equation

HRID 1132535 reaction equation
[CH:1]12[NH:2][CH:3]([CH2:7][NH:8][C:9](=[O:10])[c:11]3[cH:12][cH:13][cH:14][c:15]4[c:20]3[O:19][CH2:18][CH2:17][O:16]4)[CH2:4][CH:5]1[CH2:6]2.[NH2:21][c:22]1[s:23][cH:24][c:25](-[c:27]2[c:28]([C:29](=[O:30])[OH:31])[cH:32][cH:33][cH:34][cH:35]2)[n:26]1>>[CH:1]12[N:2]([C:29]([c:28]3[c:27](-[c:25]4[cH:24][s:23][c:22]([NH2:21])[n:26]4)[cH:35][cH:34][cH:33][cH:32]3)=[O:30])[CH:3]([CH2:7][NH:8][C:9](=[O:10])[c:11]3[cH:12][cH:13][cH:14][c:15]4[c:20]3[O:19][CH2:18][CH2:17][O:16]4)[CH2:4][CH:5]1[CH2:6]2

Participants

3

Reactant 2

HCID 14097732-(2-Amino-thiazol-4-yl)-benzoic acidHCID 178522754HCID 178522754, compound

Product 1

HCID 178508282N-[[2-[2-(2-amino-1,3-thiazol-4-yl)benzoyl]-2-azabicyclo[3.1.0]hexan-3-yl]methyl]-2,3-dihydro-1,4-benzodioxine-5-carboxamide

Sources & evidence

ORD record
ord-aece573f19864b448fd4c00fd71a968a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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