4-Fluorobenzylamine → 2-Bromo-N-(3,4-difluorobenzyl)-4-methylthiazole-5-carboxamide

HRID 1132698Notes

Reaction equation

HRID 1132698 reaction equation
[Br:20][c:21]1[s:22][c:23]([C:27](=[O:28])[OH:29])[c:24]([CH3:26])[n:25]1.[F:11][c:12]1[cH:13][cH:14][c:15]([CH2:16][NH2:17])[cH:18][cH:19]1.[F:1][c:2]1[cH:3][c:4]([CH2:9][NH2:10])[cH:5][cH:6][c:7]1[F:8]>>[F:1][c:2]1[cH:3][c:4]([CH2:9][NH:10][C:27]([c:23]2[s:22][c:21]([Br:20])[n:25][c:24]2[CH3:26])=[O:28])[cH:5][cH:6][c:7]1[F:8]

Participants

4

Reactant 3

HCID 673264-FluorobenzylamineHCID 1235723,4-DifluorobenzylamineHCID 28240582-Bromo-4-methyl-1,3-thiazole-5-carboxylic acid

Product 1

HCID 666311772-Bromo-N-(3,4-difluorobenzyl)-4-methylthiazole-5-carboxamide

Sources & evidence

ORD record
ord-754c0288985840f59792fe1bb8c86bb6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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