4-Amino-3-(trifluoromethyl)benzoic acid → 2-(1-{[4-Amino-3-(trifluoromethyl)phenyl]carbonyl}piperidin-4-yl)-5-(3,4-dimethoxyphenyl)-4,4-dimethyl-2,4-dihydro-3H-pyrazol-3-one
Reaction equation
[CH3:1][O:2][c:3]1[cH:4][c:5]([C:11]2=[N:15][N:14]([CH:16]3[CH2:17][CH2:18][NH:19][CH2:20][CH2:21]3)[C:13](=[O:22])[C:12]2([CH3:23])[CH3:24])[cH:6][cH:7][c:8]1[O:9][CH3:10].[NH2:25][c:26]1[c:27]([C:35]([F:36])([F:37])[F:38])[cH:28][c:29]([C:30](=[O:31])[OH:32])[cH:33][cH:34]1>>[CH3:1][O:2][c:3]1[cH:4][c:5]([C:11]2=[N:15][N:14]([CH:16]3[CH2:17][CH2:18][N:19]([C:30]([c:29]4[cH:28][c:27]([C:35]([F:36])([F:37])[F:38])[c:26]([NH2:25])[cH:34][cH:33]4)=[O:31])[CH2:20][CH2:21]3)[C:13](=[O:22])[C:12]2([CH3:23])[CH3:24])[cH:6][cH:7][c:8]1[O:9][CH3:10]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-3016025faeef4f7ca1898cd75cb60b0d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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