2-Morpholinoethanol → 4-[5-Bromo-2-(2-morpholin-4-yl-ethoxy)-phenyl)-6-chloro-pyrimidin-2-ylamine

HRID 1132976Notes

Reaction equation

HRID 1132976 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]([O:16][CH2:17][CH2:18][CH3:19])[c:6](-[c:8]2[n:9][c:10]([NH2:15])[n:11][c:12]([Cl:14])[cH:13]2)[cH:7]1.[NH2:20][c:21]1[n:22][c:23](-[c:24]2[cH:25][c:26]([Br:27])[cH:28][cH:29][c:30]2[OH:31])[cH:32][c:33]([Cl:34])[n:35]1.[O:36]1[CH2:37][CH2:38][N:39]([CH2:42][CH2:43][OH:44])[CH2:40][CH2:41]1>>[Br:1][c:2]1[cH:3][cH:4][c:5]([O:16][CH2:17][CH2:18][N:39]2[CH2:38][CH2:37][O:36][CH2:41][CH2:40]2)[c:6](-[c:8]2[n:9][c:10]([NH2:15])[n:11][c:12]([Cl:14])[cH:13]2)[cH:7]1

Participants

4

Reactant 3

HCID 611632-MorpholinoethanolHCID 860043744-(5-Bromo-2-propoxy-phenyl)-6-chloro-pyrimidin-2-ylamineHCID 1360800122-(2-Amino-6-chloro-pyrimidin-4-yl)-4-bromo-phenol

Product 1

HCID 865946044-[5-Bromo-2-(2-morpholin-4-yl-ethoxy)-phenyl)-6-chloro-pyrimidin-2-ylamine

Sources & evidence

ORD record
ord-1cc2da04849e4c398f9e830ef45e29cc
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

Loading…