Methanol → 2-{4-[4-Cyclopropyl-2-(4-trifluoromethoxy-phenyl)-pyrimidin-5-ylmethylsulfanyl]-2-methyl-phenoxy}-2-methyl-propionic acid ethyl ester
Reaction equation
[C:45](=[O:46])([O-:47])[O-:48].[CH2:23]([CH3:24])[O:25][C:26]([C:27]([CH3:28])([CH3:29])[O:30][c:31]1[c:32]([CH3:41])[cH:33][c:34]([S:37][C:38](=[O:39])[CH3:40])[cH:35][cH:36]1)=[O:42].[CH3:43][OH:44].[CH3:51][C:52]#[N:53].[Cl:1][CH2:2][c:3]1[c:4]([CH:20]2[CH2:21][CH2:22]2)[n:5][c:6](-[c:9]2[cH:10][cH:11][c:12]([O:15][C:16]([F:17])([F:18])[F:19])[cH:13][cH:14]2)[n:7][cH:8]1.[Cs+:49].[Cs+:50]>>[CH2:2]([c:3]1[c:4]([CH:20]2[CH2:21][CH2:22]2)[n:5][c:6](-[c:9]2[cH:10][cH:11][c:12]([O:15][C:16]([F:17])([F:18])[F:19])[cH:13][cH:14]2)[n:7][cH:8]1)[S:37][c:34]1[cH:33][c:32]([CH3:41])[c:31]([O:30][C:27]([C:26]([O:25][CH2:23][CH3:24])=[O:42])([CH3:28])[CH3:29])[cH:36][cH:35]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-06b7656a28884243852497e2142c0a21
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
Loading…