Methyl chloroformate → Methyl 3-[(3,6-diethylpyrazin-2-yl)amino]-4-(2-fluoroethoxy)pyrrolidine-1-carboxylate

HRID 1134524Notes

Reaction equation

HRID 1134524 reaction equation
[C:1]([N:2]1[CH2:3][CH:4]([O:5][CH2:6][CH3:7])[CH:8]([NH:9][c:10]2[c:11]([CH2:12][CH3:13])[n:14][c:15](-[c:16]3[cH:17][cH:18][c:19]([Cl:20])[cH:21][c:22]3[Cl:23])[c:24]([CH2:25][CH3:26])[n:27]2)[CH2:28]1)(=[O:29])[CH3:30].[CH2:31]([CH3:32])[c:33]1[c:34]([NH:41][CH:42]2[CH2:43][NH:44][CH2:45][CH:46]2[O:47][CH2:48][CH2:49][F:50])[n:35][c:36]([CH2:39][CH3:40])[cH:37][n:38]1.[Cl:51][C:52](=[O:53])[O:54][CH3:55]>>[CH2:31]([CH3:32])[c:33]1[c:34]([NH:41][CH:42]2[CH2:43][N:44]([C:52](=[O:53])[O:54][CH3:55])[CH2:45][CH:46]2[O:47][CH2:48][CH2:49][F:50])[n:35][c:36]([CH2:39][CH3:40])[cH:37][n:38]1

Participants

4

Reactant 3

HCID 6586Methyl chloroformateHCID 10238466HCID 10238466, compoundHCID 221472343,6-diethyl-N-[4-(2-fluoroethoxy)pyrrolidin-3-yl]pyrazin-2-amine

Product 1

HCID 22147306Methyl 3-[(3,6-diethylpyrazin-2-yl)amino]-4-(2-fluoroethoxy)pyrrolidine-1-carboxylate

Sources & evidence

ORD record
ord-c1b8eb2576e542988d707d22f483594a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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