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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1134649Generated: October 26, 2026

Toluene → methyl 4-[({[4-(8-azabicyclo[3.2.1]oct-8-yl)-3-(trifluoromethyl)benzyl]amino}carbonyl)amino]-1H-indazole-1-carboxylate

https://huagongshe.com/reaction/1134649

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTolueneHCID 1140—
ReactantPhosgeneHCID 6371—
ReactantTetrahydrofuranHCID 8028—
Reactantmethyl 4-amino-1H-indazole-1-carboxylateHCID 22032652—
Reactant4-(8-Azabicyclo[3.2.1]oct-8-yl)-3-(trifluoromethyl)benzylamineHCID 22337616—
Productmethyl 4-[({[4-(8-azabicyclo[3.2.1]oct-8-yl)-3-(trifluoromethyl)benzyl]amino}carbonyl)amino]-1H-indazole-1-carboxylateHCID 22337659—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-7688dae9242047cca3ac521d52603d66
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)