2-Chloronicotinic acid → ASLAN003

HRID 1134812Notes

Reaction equation

HRID 1134812 reaction equation
[Cl:18][c:19]1[c:20]([C:21](=[O:22])[OH:23])[cH:24][cH:25][cH:26][n:27]1.[F:1][c:2]1[cH:3][c:4](-[c:10]2[cH:11][c:12]([O:16][CH3:17])[cH:13][cH:14][cH:15]2)[cH:5][c:6]([F:9])[c:7]1[NH2:8]>>[F:1][c:2]1[cH:3][c:4](-[c:10]2[cH:11][c:12]([O:16][CH3:17])[cH:13][cH:14][cH:15]2)[cH:5][c:6]([F:9])[c:7]1[NH:8][c:19]1[c:20]([C:21](=[O:22])[OH:23])[cH:24][cH:25][cH:26][n:27]1

Participants

3

Reactant 2

HCID 762582-Chloronicotinic acidHCID 533754393,5-Difluoro-3′-methoxy[1,1′-biphenyl]-4-amine

Product 1

HCID 24986824ASLAN003

Sources & evidence

ORD record
ord-f53508d6f2bb410b9066c5ed6c6be013
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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