Sodium ion → tert-Butyl 4-formylpiperidine-1-carboxylate

HRID 1134924Notes

Reaction equation

[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([CH2:14][OH:15])[CH2:12][CH2:13]1.[CH2:18]([Cl:19])[Cl:20].[Na+:17].[OH-:16]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([CH:14]=[O:15])[CH2:12][CH2:13]1

Participants

Reactant 4

HCID 923Sodium ion

HCID 961Hydroxide

HCID 6344Dichloromethane

HCID 2764081Tert-butyl 4-(hydroxymethyl)piperidine-1-carboxylate

Product 1

HCID 1514430tert-Butyl 4-formylpiperidine-1-carboxylate

Sources & evidence

ORD record: ord-938ad11e627442e68d9cd3d9f875f153
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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