Sodium ion → 4-(6-bromopyrazolo[1,5-a]pyrimidin-3-yl)-N-(2,2,2-trifluoro-1-pyridin-2-ylethyl) thiophene-2-carboxamide
Reaction equation
[Br:1][c:2]1[cH:3][n:4][c:5]2[n:6]([cH:7]1)[n:8][cH:9][c:10]2[I:11].[C:40](=[O:41])([O-:42])[O-:43].[CH3:12][C:13]1([CH3:14])[C:15]([CH3:16])([CH3:17])[O:18][B:19]([c:20]2[cH:21][c:22]([C:25](=[O:26])[NH:27][CH:28]([C:29]([F:30])([F:31])[F:32])[c:33]3[n:34][cH:35][cH:36][cH:37][cH:38]3)[s:23][cH:24]2)[O:39]1.[Na+:44].[Na+:45].[O:123]1[CH2:124][CH2:125][O:126][CH2:127][CH2:128]1.[cH:46]1[cH:47][cH:48][c:49]([P:50]([Pd:51]([P:52]([c:53]2[cH:54][cH:55][cH:56][cH:57][cH:58]2)([c:59]2[cH:60][cH:61][cH:62][cH:63][cH:64]2)[c:65]2[cH:66][cH:67][cH:68][cH:69][cH:70]2)([P:71]([c:72]2[cH:73][cH:74][cH:75][cH:76][cH:77]2)([c:78]2[cH:79][cH:80][cH:81][cH:82][cH:83]2)[c:84]2[cH:85][cH:86][cH:87][cH:88][cH:89]2)[P:90]([c:91]2[cH:92][cH:93][cH:94][cH:95][cH:96]2)([c:97]2[cH:98][cH:99][cH:100][cH:101][cH:102]2)[c:103]2[cH:104][cH:105][cH:106][cH:107][cH:108]2)([c:109]2[cH:110][cH:111][cH:112][cH:113][cH:114]2)[c:115]2[cH:116][cH:117][cH:118][cH:119][cH:120]2)[cH:121][cH:122]1>>[Br:1][c:2]1[cH:3][n:4][c:5]2[n:6]([cH:7]1)[n:8][cH:9][c:10]2-[c:20]1[cH:21][c:22]([C:25](=[O:26])[NH:27][CH:28]([C:29]([F:30])([F:31])[F:32])[c:33]2[n:34][cH:35][cH:36][cH:37][cH:38]2)[s:23][cH:24]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-b46e9853bf754b04aaeeeec516891388
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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