2,4-Dichloro-5-(trifluoromethyl)pyrimidine → Tert-butyl 1-(4-(4-chloro-5-(trifluoromethyl)pyrimidin-2-ylamino)phenyl)ethylcarbamate

HRID 1135076Notes

Reaction equation

HRID 1135076 reaction equation
[Cl:18][c:19]1[n:20][cH:21][c:22]([C:26]([F:27])([F:28])[F:29])[c:23]([Cl:25])[n:24]1.[NH2:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([CH3:9])[NH:10][C:11]([O:12][C:13]([CH3:14])([CH3:15])[CH3:16])=[O:17])[cH:6][cH:7]1>>[NH:1]([c:2]1[cH:3][cH:4][c:5]([CH:8]([CH3:9])[NH:10][C:11]([O:12][C:13]([CH3:14])([CH3:15])[CH3:16])=[O:17])[cH:6][cH:7]1)[c:19]1[n:20][cH:21][c:22]([C:26]([F:27])([F:28])[F:29])[c:23]([Cl:25])[n:24]1

Participants

3

Reactant 2

HCID 27827742,4-Dichloro-5-(trifluoromethyl)pyrimidineHCID 22569414tert-butyl N-[1-(4-aminophenyl)ethyl]carbamate

Product 1

HCID 76611269Tert-butyl 1-(4-(4-chloro-5-(trifluoromethyl)pyrimidin-2-ylamino)phenyl)ethylcarbamate

Sources & evidence

ORD record
ord-69f110e01dd7437db6f14dc39c03397c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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