4-(Tetrahydropyran-4-yloxymethyl)-benzenesulfonyl chloride → N-[1-(4-Amino-thieno[3,2-c]pyridin-2-ylmethyl)-2-(4-methyl-piperidin-1-yl)-2-oxo-ethyl]-4-(tetrahydropyran-4-yloxymethyl)-benzenesulfonamide
Reaction equation
[NH2:19][c:20]1[n:21][cH:22][cH:23][c:24]2[c:25]1[cH:26][c:27]([CH2:29][CH:30]([C:31](=[O:32])[N:33]1[CH2:34][CH2:35][CH:36]([CH3:39])[CH2:37][CH2:38]1)[NH:40][S:41]([c:42]1[cH:43][cH:44][c:45]([O:46][CH:47]3[CH2:48][CH2:49][O:50][CH2:51][CH2:52]3)[cH:53][cH:54]1)(=[O:55])=[O:56])[s:28]2.[O:1]1[CH2:2][CH2:3][CH:4]([O:7][CH2:8][c:9]2[cH:10][cH:11][c:12]([S:15](=[O:16])(=[O:17])[Cl:18])[cH:13][cH:14]2)[CH2:5][CH2:6]1>>[O:1]1[CH2:2][CH2:3][CH:4]([O:7][CH2:8][c:9]2[cH:10][cH:11][c:12]([S:15](=[O:16])(=[O:17])[NH:40][CH:30]([CH2:29][c:27]3[cH:26][c:25]4[c:20]([NH2:19])[n:21][cH:22][cH:23][c:24]4[s:28]3)[C:31](=[O:32])[N:33]3[CH2:34][CH2:35][CH:36]([CH3:39])[CH2:37][CH2:38]3)[cH:13][cH:14]2)[CH2:5][CH2:6]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-00ccffc8faf94c6aab0289f2957a1b8f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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