3-Aminophenol → 5-fluoro-N2-(3-hydroxyphenyl)-N4-(3-trifluoromethoxyphenyl)-2,4-pyrimidinediamine

HRID 1135427Notes

Reaction equation

HRID 1135427 reaction equation
[Cl:9][c:10]1[n:11][cH:12][c:13]([F:28])[c:14]([NH:16][c:17]2[cH:18][c:19]([O:23][C:24]([F:25])([F:26])[F:27])[cH:20][cH:21][cH:22]2)[n:15]1.[OH:1][c:2]1[cH:3][c:4]([NH2:5])[cH:6][cH:7][cH:8]1>>[OH:1][c:2]1[cH:3][c:4]([NH:5][c:10]2[n:11][cH:12][c:13]([F:28])[c:14]([NH:16][c:17]3[cH:18][c:19]([O:23][C:24]([F:25])([F:26])[F:27])[cH:20][cH:21][cH:22]3)[n:15]2)[cH:6][cH:7][cH:8]1

Participants

3

Reactant 2

HCID 115683-AminophenolHCID 220605992-chloro-5-fluoro-N4-(3-trifluoromethoxyphenyl)-4-pyrimidineamine

Product 1

HCID 220610035-fluoro-N2-(3-hydroxyphenyl)-N4-(3-trifluoromethoxyphenyl)-2,4-pyrimidinediamine

Sources & evidence

ORD record
ord-3b74cef05ecd4dcba2e8f7e57b84ec7d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

Loading…