Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1135439Generated: October 25, 2026

Dimethylformamide → N-[(4-chlorophenyl)methyl]-8-(4-hydroxypent-1-ynyl)-1-methyl-6-(morpholinomethyl)-4-oxo-quinoline-3-carboxamide

https://huagongshe.com/reaction/1135439

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantDiethylamineHCID 8021—
ReactantTriphenylphosphineHCID 11776—
ReactantPalladium ChlorideHCID 24290—
ReactantCopper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 24350—
Reactant4-Pentyn-2-olHCID 92915—
ReactantN-(4-chlorobenzyl)-8-iodo-1-methyl-6-(4-morpholinylmethyl)-4-oxo-1,4-dihydro-3-quinolinecarboxamideHCID 12095879—
ProductN-[(4-chlorophenyl)methyl]-8-(4-hydroxypent-1-ynyl)-1-methyl-6-(morpholinomethyl)-4-oxo-quinoline-3-carboxamideHCID 5278423—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-abc569a111924cee8497bbe6f2b838dc
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)