Pyridine → Isopropyl 5-[acetyl-(3,5-bistrifluoromethylbenzyl)amino]-8-bromo-2,3,4,5-tetrahydrobenzo[b]azepine-1-carboxylate
Reaction equation
[CH3:1][C:2](=[O:3])[O:4][C:5](=[O:6])[CH3:7].[Cl:48][CH2:49][Cl:50].[F:8][C:9]([c:10]1[cH:11][c:12]([CH2:13][NH:14][CH:15]2[c:16]3[c:17]([cH:28][c:29]([Br:32])[cH:30][cH:31]3)[N:18]([C:22](=[O:23])[O:24][CH:25]([CH3:26])[CH3:27])[CH2:19][CH2:20][CH2:21]2)[cH:33][c:34]([C:36]([F:37])([F:38])[F:39])[cH:35]1)([F:40])[F:41].[cH:42]1[cH:43][cH:44][n:45][cH:46][cH:47]1>>[CH3:1][C:2](=[O:3])[N:14]([CH2:13][c:12]1[cH:11][c:10]([C:9]([F:8])([F:40])[F:41])[cH:35][c:34]([C:36]([F:37])([F:38])[F:39])[cH:33]1)[CH:15]1[c:16]2[c:17]([cH:28][c:29]([Br:32])[cH:30][cH:31]2)[N:18]([C:22](=[O:23])[O:24][CH:25]([CH3:26])[CH3:27])[CH2:19][CH2:20][CH2:21]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-d96cc76798c2455d95d6ee41fcdabcb6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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