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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 113672Generated: October 25, 2026

Dichloromethane → 2-[1-(3,5-Dichloro-2-hydroxy-benzyl)-4-fluoro-piperidin-4-ylmethyl]-isoindole-1,3-dione

https://huagongshe.com/reaction/113672

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantTrifluoroacetic acidHCID 6422—
ReactantTriethylamineHCID 8471—
Reactant3,5-DichlorosalicylaldehydeHCID 66660—
Reactant2-(4-Fluoro-piperidin-4-ylmethyl)-isoindole-1,3-dioneHCID 23069265—
Product2-[1-(3,5-Dichloro-2-hydroxy-benzyl)-4-fluoro-piperidin-4-ylmethyl]-isoindole-1,3-dioneHCID 69069418—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-e85eb9fc9fa84b6fadc1410a338db25e
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)