2-amino-5-(4-hydroxycyclohexyl)-N,N-dimethylbenzamide → Diethyl (4-{[4-{[2-(dimethylcarbamoyl)-4-(trans-4-hydroxycyclohexyl) phenyl]amino}-5-(trifluoromethyl) pyrimidin-2-yl]amino}-3-methoxybenzyl)phosphonate
Reaction equation
[Cl:1][c:2]1[n:3][c:4]([NH:12][c:13]2[c:14]([O:28][CH3:29])[cH:15][c:16]([CH2:17][P:18]([O:19][CH2:20][CH3:21])([O:22][CH2:23][CH3:24])=[O:25])[cH:26][cH:27]2)[n:5][cH:6][c:7]1[C:8]([F:9])([F:10])[F:11].[NH2:30][c:31]1[c:32]([C:33](=[O:34])[N:35]([CH3:36])[CH3:37])[cH:38][c:39]([CH:42]2[CH2:43][CH2:44][CH:45]([OH:48])[CH2:46][CH2:47]2)[cH:40][cH:41]1>>[c:2]1([NH:30][c:31]2[c:32]([C:33](=[O:34])[N:35]([CH3:36])[CH3:37])[cH:38][c:39]([CH:42]3[CH2:43][CH2:44][CH:45]([OH:48])[CH2:46][CH2:47]3)[cH:40][cH:41]2)[n:3][c:4]([NH:12][c:13]2[c:14]([O:28][CH3:29])[cH:15][c:16]([CH2:17][P:18]([O:19][CH2:20][CH3:21])([O:22][CH2:23][CH3:24])=[O:25])[cH:26][cH:27]2)[n:5][cH:6][c:7]1[C:8]([F:9])([F:10])[F:11]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-5860a1d355c848df86e2e9565b46b1b9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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