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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1137096Generated: November 1, 2026

Tetrahydrofuran → N-[5-tert-butyl-3-[(1-hydroxycyclobutyl)methyl]-1,3-thiazol-2-ylidene]-5-cyano-2-methoxybenzamide

https://huagongshe.com/reaction/1137096

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTetrahydrofuranHCID 8028—
ReactantTriethylamineHCID 8471—
ReactantThionyl ChlorideHCID 24386—
Reactant5-Cyano-2-methoxybenzoic acidHCID 21942568—
Reactant1-((5-tert-butyl-2-iminothiazol-3(2H)-yl)methyl)cyclobutanolHCID 66852014—
ProductN-[5-tert-butyl-3-[(1-hydroxycyclobutyl)methyl]-1,3-thiazol-2-ylidene]-5-cyano-2-methoxybenzamideHCID 66852270—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-7cde33218a2c43f8af50137dda46ee54
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)