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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 11373Generated: October 27, 2026

trans-2-Phenyl-1-cyclopropanecarbonyl chloride → (1R*,2R*)-N-{3-[4-amino-2,6,7-trimethyl-1H-imidazo[4,5-c]pyridin-1-yl]propyl}-2-phenylcyclopropanecarboxamide

https://huagongshe.com/reaction/11373

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttrans-2-Phenyl-1-cyclopropanecarbonyl chlorideHCID 13656—
Reactant1-(3-aminopropyl)-2,6,7-trimethyl-1H-imidazo[4,5-c]pyridin-4-amineHCID 21946031—
Product(1R*,2R*)-N-{3-[4-amino-2,6,7-trimethyl-1H-imidazo[4,5-c]pyridin-1-yl]propyl}-2-phenylcyclopropanecarboxamideHCID 59049849—

Reaction Steps

Using the method of Examples 78–92, trans-2-phenyl-1-cyclopropanecarbonyl chloride was reacted with 1-(3-aminopropyl)-2,6,7-trimethyl-1H-imidazo[4,5-c]pyridin-4-amine to provide the desired product. The observed accurate mass was 378.2298.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07098221B2
Source datasetuspto-grants-2006_08
ORD IDord-d63943723ec344abb2ab368b9531d738
Source noteuspto-grants-2006_08