Sodium ion → Tert-butyl 1-(3-chloropyridin-2-yl)-3,3-difluorocyclobutanecarboxylate
Reaction equation
[CH3:22][Si:23]([CH3:24])([CH3:25])[N-:26][Si:27]([CH3:28])([CH3:29])[CH3:30].[CH3:32][c:33]1[cH:34][cH:35][cH:36][cH:37][cH:38]1.[Cl:1][c:2]1[c:3]([F:8])[n:4][cH:5][cH:6][cH:7]1.[F:9][C:10]1([F:21])[CH2:11][CH:12]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:13]1.[Na+:31]>>[Cl:1][c:2]1[c:3]([C:12]2([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:11][C:10]([F:9])([F:21])[CH2:13]2)[n:4][cH:5][cH:6][cH:7]1Participants
6
Sources & evidence
- ORD record
- ord-d7c11ffd06b04b9d8d53d0f9a956e065
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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