1-(4-Chlorophenyl)cyclohexanecarboxylic acid → 1-(4-chlorophenyl)-N-(3-{4-[6-(isobutyrylamino)-2-pyridinyl]-1-piperidinyl}propyl)cyclohexanecarboxamide

HRID 1137670Notes

Reaction equation

HRID 1137670 reaction equation
[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:8]2([C:14](=[O:15])[OH:16])[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13]2)[cH:6][cH:7]1.[NH2:17][CH2:18][CH2:19][CH2:20][N:21]1[CH2:22][CH2:23][CH:24]([c:27]2[cH:28][cH:29][cH:30][c:31]([NH:33][C:34]([CH:35]([CH3:36])[CH3:37])=[O:38])[n:32]2)[CH2:25][CH2:26]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:8]2([C:14](=[O:16])[NH:17][CH2:18][CH2:19][CH2:20][N:21]3[CH2:22][CH2:23][CH:24]([c:27]4[cH:28][cH:29][cH:30][c:31]([NH:33][C:34]([CH:35]([CH3:36])[CH3:37])=[O:38])[n:32]4)[CH2:25][CH2:26]3)[CH2:9][CH2:10][CH2:11][CH2:12][CH2:13]2)[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 1008731-(4-Chlorophenyl)cyclohexanecarboxylic acidHCID 21957182N-{6-[1-(3-aminopropyl)-4-piperidinyl]-2-pyridinyl}2-methylpropanamide

Product 1

HCID 219571561-(4-chlorophenyl)-N-(3-{4-[6-(isobutyrylamino)-2-pyridinyl]-1-piperidinyl}propyl)cyclohexanecarboxamide

Sources & evidence

ORD record
ord-258514ba0ab44484b82d22fbbc75d36b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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