3-(4-Methyl-1-piperazine)propan-1-ol → N-(4-chloro-3-(1-(3-(4-methylpiperazin-1-yl)propyl)-1H-1,2,4-triazol-3-yl)thiophen-2-yl)-2-(2-oxo-6-(trifluoromethyl)quinolin-1(2H)-yl)acetamide

HRID 1137829Notes

Reaction equation

HRID 1137829 reaction equation
[CH3:31][N:32]1[CH2:33][CH2:34][N:35]([CH2:38][CH2:39][CH2:40][OH:41])[CH2:36][CH2:37]1.[Cl:1][c:2]1[c:3](-[c:26]2[n:27][nH:28][cH:29][n:30]2)[c:4]([NH:7][C:8]([CH2:9][n:10]2[c:11](=[O:24])[cH:12][cH:13][c:14]3[cH:15][c:16]([C:20]([F:21])([F:22])[F:23])[cH:17][cH:18][c:19]23)=[O:25])[s:5][cH:6]1>>[Cl:1][c:2]1[c:3](-[c:26]2[n:27][n:28]([CH2:40][CH2:39][CH2:38][N:35]3[CH2:34][CH2:33][N:32]([CH3:31])[CH2:37][CH2:36]3)[cH:29][n:30]2)[c:4]([NH:7][C:8]([CH2:9][n:10]2[c:11](=[O:24])[cH:12][cH:13][c:14]3[cH:15][c:16]([C:20]([F:21])([F:22])[F:23])[cH:17][cH:18][c:19]23)=[O:25])[s:5][cH:6]1

Participants

3

Reactant 2

HCID 792083-(4-Methyl-1-piperazine)propan-1-olHCID 178521249HCID 178521249, compound

Product 1

HCID 46869227N-(4-chloro-3-(1-(3-(4-methylpiperazin-1-yl)propyl)-1H-1,2,4-triazol-3-yl)thiophen-2-yl)-2-(2-oxo-6-(trifluoromethyl)quinolin-1(2H)-yl)acetamide

Sources & evidence

ORD record
ord-dd4e15f649da4f469096623adec3bbc6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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