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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 113783Generated: October 31, 2026

1,4-Dioxane → 1-(5-chlorothiophen-2-ylsulfonyl)-3-(4-(6-fluoro-7-(methylamino)-4-oxo-2H-benzo[e][1,3]oxazin-3(4H)-yl)phenyl)urea

https://huagongshe.com/reaction/113783

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,4-DioxaneHCID 31275—
Reactant3-(4-Aminophenyl)-6-fluoro-7-(methylamino)-2,3-dihydrobenzo[e][1,3]oxazin-4-oneHCID 18452486—
ReactantEthyl ((5-chlorothiophen-2-yl)sulfonyl)carbamateHCID 24778122—
Product1-(5-chlorothiophen-2-ylsulfonyl)-3-(4-(6-fluoro-7-(methylamino)-4-oxo-2H-benzo[e][1,3]oxazin-3(4H)-yl)phenyl)ureaHCID 11627632—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-e707b85daeed431e85a97ed88a1086dc
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)