tert-Butyl 3-ethylpiperazine-1-carboxylate → 4-[3-(2-Chloro-pyrimidin-4-yl)-benzyl]-3-ethyl-piperazine-1-carboxylic acid tert-butyl ester

HRID 1138041Notes

Reaction equation

HRID 1138041 reaction equation
[C:16]([CH3:17])([CH3:18])([CH3:19])[O:20][C:21](=[O:22])[N:23]1[CH2:24][CH:25]([CH2:29][CH3:30])[NH:26][CH2:27][CH2:28]1.[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[cH:9][c:10]([CH:11]=[O:12])[cH:13][cH:14][cH:15]2)[n:7]1>>[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[cH:9][c:10]([CH2:11][N:26]3[CH:25]([CH2:29][CH3:30])[CH2:24][N:23]([C:21]([O:20][C:16]([CH3:17])([CH3:18])[CH3:19])=[O:22])[CH2:28][CH2:27]3)[cH:13][cH:14][cH:15]2)[n:7]1

Participants

3

Reactant 2

HCID 22219867tert-Butyl 3-ethylpiperazine-1-carboxylateHCID 249019653-(2-Chloro-pyrimidin-4-yl)-benzaldehyde

Product 1

HCID 866033064-[3-(2-Chloro-pyrimidin-4-yl)-benzyl]-3-ethyl-piperazine-1-carboxylic acid tert-butyl ester

Sources & evidence

ORD record
ord-5f59dd14a637408287511ca9ed715405
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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