1-(3,5-Dichloropyridin-2-yl)piperazine → 5-Chloro-2-[4-(3,5-dichloro-pyridin-2-yl)-piperazin-1-yl]-6-trifluoromethyl-1H-benzoimidazole
Reaction equation
[Cl:16][c:17]1[c:18]([N:24]2[CH2:25][CH2:26][NH:27][CH2:28][CH2:29]2)[n:19][cH:20][c:21]([Cl:23])[cH:22]1.[Cl:1][c:2]1[nH:3][c:4]2[c:5]([n:6]1)[cH:7][c:8]([C:12]([F:13])([F:14])[F:15])[c:9]([Cl:11])[cH:10]2>>[c:2]1([N:27]2[CH2:26][CH2:25][N:24]([c:18]3[c:17]([Cl:16])[cH:22][c:21]([Cl:23])[cH:20][n:19]3)[CH2:29][CH2:28]2)[n:3][c:4]2[c:5]([nH:6]1)[cH:7][c:8]([C:12]([F:13])([F:14])[F:15])[c:9]([Cl:11])[cH:10]2Participants
3
Sources & evidence
- ORD record
- ord-5222c4b243da4c80a6068f62c9bcb777
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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