N-tert-butyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene-2-sulfonamide → 5-[4-(3-Methoxy-4-trifluoromethyl-phenyl)-6-methyl-[2,4']bipyridinyl-2'-yl]-thiophene-2-sulfonic acid tert-butylamide

HRID 1138534Notes

Reaction equation

HRID 1138534 reaction equation
[C:27]([CH3:28])([CH3:29])([CH3:30])[NH:31][S:32](=[O:33])(=[O:34])[c:35]1[s:36][c:37]([B:40]2[O:41][C:42]([CH3:43])([CH3:44])[C:45]([CH3:46])([CH3:47])[O:48]2)[cH:38][cH:39]1.[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[n:9][c:10]([CH3:26])[cH:11][c:12](-[c:14]3[cH:15][c:16]([O:24][CH3:25])[c:17]([C:20]([F:21])([F:22])[F:23])[cH:18][cH:19]3)[cH:13]2)[cH:7]1>>[c:2]1(-[c:37]2[s:36][c:35]([S:32]([NH:31][C:27]([CH3:28])([CH3:29])[CH3:30])(=[O:33])=[O:34])[cH:39][cH:38]2)[n:3][cH:4][cH:5][c:6](-[c:8]2[n:9][c:10]([CH3:26])[cH:11][c:12](-[c:14]3[cH:15][c:16]([O:24][CH3:25])[c:17]([C:20]([F:21])([F:22])[F:23])[cH:18][cH:19]3)[cH:13]2)[cH:7]1

Participants

3

Reactant 2

HCID 57468817N-tert-butyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)thiophene-2-sulfonamideHCID 866154482'-Chloro-4-(3-methoxy-4-trifluoromethylphenyl)-6-methyl-[2,4']bipyridinyl

Product 1

HCID 247599495-[4-(3-Methoxy-4-trifluoromethyl-phenyl)-6-methyl-[2,4']bipyridinyl-2'-yl]-thiophene-2-sulfonic acid tert-butylamide

Sources & evidence

ORD record
ord-3a0d3454efc84c939f2eb6cd5caef48d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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