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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1138891Generated: November 3, 2026

2-Fluoro-5-(trifluoromethyl)phenyl isocyanate → 1-(4-(3-Amino-2-oxo-1,2-dihydropyrido[2,3-b]pyrazin-8-yloxy)naphthalen-1-yl)-3-(2-fluoro-5-(trifluoromethyl)phenyl)urea

https://huagongshe.com/reaction/1138891

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Fluoro-5-(trifluoromethyl)phenyl isocyanateHCID 2733380—
Reactant3-amino-8-(4-aminonaphthalen-1-yloxy)pyrido[2,3-b]pyrazin-2(1H)-oneHCID 46901252—
Product1-(4-(3-Amino-2-oxo-1,2-dihydropyrido[2,3-b]pyrazin-8-yloxy)naphthalen-1-yl)-3-(2-fluoro-5-(trifluoromethyl)phenyl)ureaHCID 44132374—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-7cc6343ac0d240dbab844a59c6d65159
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)