Ethyl 5-(4-(difluoromethoxy)phenyl)-1,3,4-oxadiazole-2-carboxylate → (3-(4-(2-Oxa-6-azaspiro[3.3]heptan-6-ylmethyl)phenoxy)azetidin-1-yl)(5-(4-(difluoromethoxy)phenyl)-1,3,4-oxadiazol-2-yl)methanone
Reaction equation
[F:1][CH:2]([O:3][c:4]1[cH:5][cH:6][c:7](-[c:10]2[n:11][n:12][c:13]([C:15]([O:17][CH2:16][CH3:18])=[O:19])[o:14]2)[cH:8][cH:9]1)[F:20].[NH:21]1[CH2:22][CH:23]([O:25][c:26]2[cH:27][cH:28][c:29]([CH2:30][N:31]3[CH2:32][C:33]4([CH2:34][O:35][CH2:36]4)[CH2:37]3)[cH:38][cH:39]2)[CH2:24]1>>[F:1][CH:2]([O:3][c:4]1[cH:5][cH:6][c:7](-[c:10]2[n:11][n:12][c:13]([C:15](=[O:17])[N:21]3[CH2:22][CH:23]([O:25][c:26]4[cH:27][cH:28][c:29]([CH2:30][N:31]5[CH2:32][C:33]6([CH2:34][O:35][CH2:36]6)[CH2:37]5)[cH:38][cH:39]4)[CH2:24]3)[o:14]2)[cH:8][cH:9]1)[F:20]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-427c14c5e1944c0e948732585ba00f1d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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