5-Fluoro-2-methylbenzenesulphonyl chloride → N-{3-[5-(2-Amino-4-pyrimidinyl)-2-(1,1-dimethylethyl)-1,3-thiazol-4-yl]-2-fluorophenyl}-5-fluoro-2-methylbenzenesulfonamide
Reaction equation
[CH3:25][c:26]1[c:27]([S:33](=[O:34])(=[O:35])[Cl:36])[cH:28][c:29]([F:32])[cH:30][cH:31]1.[NH2:1][c:2]1[c:3]([F:24])[c:4](-[c:8]2[n:9][c:10]([C:20]([CH3:21])([CH3:22])[CH3:23])[s:11][c:12]2-[c:13]2[n:14][c:15]([NH2:19])[n:16][cH:17][cH:18]2)[cH:5][cH:6][cH:7]1>>[NH:1]([c:2]1[c:3]([F:24])[c:4](-[c:8]2[n:9][c:10]([C:20]([CH3:21])([CH3:22])[CH3:23])[s:11][c:12]2-[c:13]2[n:14][c:15]([NH2:19])[n:16][cH:17][cH:18]2)[cH:5][cH:6][cH:7]1)[S:33]([c:27]1[c:26]([CH3:25])[cH:31][cH:30][c:29]([F:32])[cH:28]1)(=[O:34])=[O:35]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-e0025a7774584feabda44cf13cabbf65
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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