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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1139899Generated: November 2, 2026

Potassium Cation → 4-[7-Chloro-1-oxo-2-(4-trifluoromethoxy-benzyl)-2,3-dihydro-1H-isoindol-5-ylmethyl]-piperidine-1-carboxylic acid tert-butyl ester

https://huagongshe.com/reaction/1139899

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CationHCID 813—
ReactantSodium ionHCID 923—
ReactantHydroxideHCID 961—
ReactantWaterHCID 962—
ReactantDimethylformamideHCID 6228—
ReactantCarbonate IonHCID 19660—
Reactant9-Borabicyclo(3.3.1)nonaneHCID 78966—
Reactant1-Boc-4-MethylenepiperidineHCID 2756808—
Reactant5-Bromo-7-chloro-2-(4-trifluoromethoxybenzyl)-2,3-dihydroisoindol-1-oneHCID 11704475—
Product4-[7-Chloro-1-oxo-2-(4-trifluoromethoxy-benzyl)-2,3-dihydro-1H-isoindol-5-ylmethyl]-piperidine-1-carboxylic acid tert-butyl esterHCID 57949697—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-f6470761d6584e2f9186e4ccd1cd2a0f
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)