Ethanol → (1RS,2SR)-2-amino-1-(3,4-difluorophenyl)-3-(4-(trifluoromethyl)phenyl)-1-propanol
Reaction equation
[CH3:28][CH2:29][OH:30].[F:1][c:2]1[cH:3][c:4]([CH:9]2[CH:10]([CH2:15][c:16]3[cH:17][cH:18][c:19]([C:22]([F:23])([F:24])[F:25])[cH:20][cH:21]3)[NH:11][C:12](=[O:14])[O:13]2)[cH:5][cH:6][c:7]1[F:8].[Na+:27].[OH-:26]>>[F:1][c:2]1[cH:3][c:4]([CH:9]([CH:10]([NH2:11])[CH2:15][c:16]2[cH:17][cH:18][c:19]([C:22]([F:23])([F:24])[F:25])[cH:20][cH:21]2)[OH:13])[cH:5][cH:6][c:7]1[F:8]Participants
5
Sources & evidence
- ORD record
- ord-d1ee07d791aa4ee6b51072850f1278dd
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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