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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1140201Generated: November 1, 2026

Triphenylphosphine → 5-(3-Dimethylamino-prop-1-ynyl)-7-methyl-2-(4-trifluoromethoxy-benzyl)-2,3-dihydro-isoindol-1-one

https://huagongshe.com/reaction/1140201

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTriphenylphosphineHCID 11776—
ReactantPalladium ChlorideHCID 24290—
ReactantN,N-DimethylpropargylamineHCID 81643—
ReactantCopper iodideHCID 83717—
ReactantHCID 11560384HCID 11560384—
Product5-(3-Dimethylamino-prop-1-ynyl)-7-methyl-2-(4-trifluoromethoxy-benzyl)-2,3-dihydro-isoindol-1-oneHCID 11697021—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (7/10)
ORD IDord-e3a521bb59ab45398a2693821c9a4339
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (7/10)