Dimethyl Sulfoxide → Ethyl 5-[methyl(propan-2-yl)amino]-2-[2-oxo-3-(phenylmethoxycarbonylamino)pyrrolidin-1-yl]cyclohexane-1-carboxylate

HRID 1140273Notes

Reaction equation

HRID 1140273 reaction equation
[BH4-:35].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[NH:11][CH:12]1[C:13](=[O:29])[N:14]([CH:17]2[CH:18]([C:24](=[O:25])[O:26][CH2:27][CH3:28])[CH2:19][C:20](=[O:23])[CH2:21][CH2:22]2)[CH2:15][CH2:16]1.[CH2:39]([Cl:40])[Cl:41].[CH3:42][CH2:43][CH2:44][CH2:45][CH2:46][CH3:47].[CH3:48][OH:49].[CH3:50][S:51]([CH3:52])=[O:53].[CH:30]([CH3:31])([CH3:32])[NH:33][CH3:34].[Na+:36].[Na+:38].[OH-:37]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[NH:11][CH:12]1[C:13](=[O:29])[N:14]([CH:17]2[CH:18]([C:24](=[O:25])[O:26][CH2:27][CH3:28])[CH2:19][CH:20]([N:33]([CH:30]([CH3:31])[CH3:32])[CH3:34])[CH2:21][CH2:22]2)[CH2:15][CH2:16]1

Participants

10

Reactant 9

HCID 679Dimethyl SulfoxideHCID 887MethanolHCID 923Sodium ion2×HCID 961HydroxideHCID 6344DichloromethaneHCID 8058HexaneHCID 28123BorohydrideHCID 78485N-MethylisopropylamineHCID 178469307HCID 178469307, compound

Product 1

HCID 21075011Ethyl 5-[methyl(propan-2-yl)amino]-2-[2-oxo-3-(phenylmethoxycarbonylamino)pyrrolidin-1-yl]cyclohexane-1-carboxylate

Sources & evidence

ORD record
ord-0c343311a32e41d198ae3bb29aef3b4d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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