Dimethyl Sulfoxide → N-(5-Chloro-1,3-thiazol-2-yl)-3-cyano-N-(2,4-dimethoxybenzyl)-4-(4-fluoro-2-iodophenoxy)benzenesulfonamide
Reaction equation
[C:40](=[O:41])([O-:42])[O-:43].[CH3:47][S:48](=[O:49])[CH3:50].[Cl:1][c:2]1[cH:3][n:4][c:5]([N:7]([S:8](=[O:9])(=[O:10])[c:11]2[cH:12][c:13]([C:18]#[N:19])[c:14]([F:17])[cH:15][cH:16]2)[CH2:20][c:21]2[c:22]([O:29][CH3:30])[cH:23][c:24]([O:27][CH3:28])[cH:25][cH:26]2)[s:6]1.[I:31][c:32]1[c:33]([OH:39])[cH:34][cH:35][c:36]([F:38])[cH:37]1.[K+:44].[K+:45].[OH2:46]>>[Cl:1][c:2]1[cH:3][n:4][c:5]([N:7]([S:8](=[O:9])(=[O:10])[c:11]2[cH:12][c:13]([C:18]#[N:19])[c:14]([O:39][c:33]3[c:32]([I:31])[cH:37][c:36]([F:38])[cH:35][cH:34]3)[cH:15][cH:16]2)[CH2:20][c:21]2[c:22]([O:29][CH3:30])[cH:23][c:24]([O:27][CH3:28])[cH:25][cH:26]2)[s:6]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-d63dbc1a3a364ac5a3515157d4d0667f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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