Glycine, N-[(1,1-dimethylethoxy)carbonyl]-N-methyl- → {[[3-(2-Chloro-pyrimidin-4-yl)-benzyl]-(2-hydroxy-1-methyl-ethyl)-carbamoyl]-methyl}-methyl-carbamic acid tert-butyl ester

HRID 1140870Notes

Reaction equation

HRID 1140870 reaction equation
[C:20]([CH3:21])([CH3:22])([CH3:23])[O:24][C:25](=[O:26])[N:27]([CH3:28])[CH2:29][C:30](=[O:31])[OH:32].[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[cH:9][c:10]([CH2:11][NH:12][CH:13]([CH2:14][OH:15])[CH3:16])[cH:17][cH:18][cH:19]2)[n:7]1>>[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[cH:9][c:10]([CH2:11][N:12]([CH:13]([CH2:14][OH:15])[CH3:16])[C:30]([CH2:29][N:27]([C:25]([O:24][C:20]([CH3:21])([CH3:22])[CH3:23])=[O:26])[CH3:28])=[O:31])[cH:17][cH:18][cH:19]2)[n:7]1

Participants

3

Reactant 2

HCID 83692Glycine, N-[(1,1-dimethylethoxy)carbonyl]-N-methyl-HCID 87247278HCID 87247278, compound

Product 1

HCID 86603287{[[3-(2-Chloro-pyrimidin-4-yl)-benzyl]-(2-hydroxy-1-methyl-ethyl)-carbamoyl]-methyl}-methyl-carbamic acid tert-butyl ester

Sources & evidence

ORD record
ord-3e7b58baa3e647b18cb193fb7aa834c1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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