(Pyrimidin-5-yl)boronic acid → N-methyl-1-((4-morpholino-2-(pyrimidin-5-yl)thieno[2,3-d]pyrimidin-6-yl)methyl)piperidine-4-carboxamide
Reaction equation
[Cl:1][c:2]1[n:3][c:4]([N:22]2[CH2:23][CH2:24][O:25][CH2:26][CH2:27]2)[c:5]2[c:6]([n:7]1)[s:8][c:9]([CH2:11][N:12]1[CH2:13][CH2:14][CH:15]([C:18](=[O:19])[NH:20][CH3:21])[CH2:16][CH2:17]1)[cH:10]2.[n:28]1[cH:29][n:30][cH:31][c:32]([B:34]([OH:35])[OH:36])[cH:33]1>>[c:2]1(-[c:32]2[cH:31][n:30][cH:29][n:28][cH:33]2)[n:3][c:4]([N:22]2[CH2:23][CH2:24][O:25][CH2:26][CH2:27]2)[c:5]2[c:6]([n:7]1)[s:8][c:9]([CH2:11][N:12]1[CH2:13][CH2:14][CH:15]([C:18](=[O:19])[NH:20][CH3:21])[CH2:16][CH2:17]1)[cH:10]2Participants
3
Sources & evidence
- ORD record
- ord-8310892f9e0a488481b8b545708485bd
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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